According to the cause, wrinkles on the face are divided into three kinds. Facial expression muscles cause the wrinkles when we make a facial look. The gravity is one of the reasons for the drooping wrinkles. And, according to the skin aging itself, fine lines occur generally or topically. The forehead wrinkles, which are typical thick lines on the face, fine wrinkles below the eyes, crow's feet, the wrinkles in the middle of the forehead and the nasolabial lines are produced by facial expression muscles. Botox can block the muscles activity to resolve the wrinkles.